Product Name :
3,4-Dihydroxyphenyl Ethanol (CAS 10597-60-1)
Synonym :
2-(3,4-Dihydroxyphenyl)ethyl alcohol; 3-Hydroxytyrosol
Application :
3,4-Dihydroxyphenyl Ethanol is a phenolic antioxidant inhibitor of 5-LO (5-lipoxygenase) and 12-LO (12-lipoxygenase)
CAS:
10597-60-1
Purity:
≥98%
Molecular Weight:
154.16
Formula :
C8H10O3
Physical state:
Liquid
solubility :
Soluble in water (50mg/ml)
Shipping Condition :
Store at -20° C
Melting point:
SMILES:
C1=CC(=C(C=C1CCO)O)O
References:
:Biological effects of hydroxytyrosol, a polyphenol from olive oil endowed with antioxidant activity. | Manna, C., et al. 1999. Adv Exp Med Biol. 472: 115-30. PMID: 10736621Activity of olive oil phenols on lymphomonocyte cytosolic calcium. | Palmerini, CA., et al. 2005. J Nutr Biochem. 16: 109-13. PMID: 15681170Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.150629-67-7 Formula | Guichard, C., et al. 2006. Carcinogenesis. 27: 1812-27. PMID: 16524888Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts. | Cornwell, DG. and Ma, J. 2008. J Agric Food Chem. 56: 8774-86. PMID: 18783241Spectroscopic studies of intramolecular proton transfer in 2-(4-fluorophenylamino)-5-(2,4-dihydroxybenzeno)-1,3,4-thiadiazole. | Gagoś, M., et al. 2011. J Fluoresc. 21: 1-10. PMID: 20535632Naturally occurring hydroxytyrosol: synthesis and anticancer potential. | Bernini, R., et al. 2013. Curr Med Chem. 20: 655-70. PMID: 232445833,4 dihydroxyphenyl ethanol reduces secretion of angiogenin in human retinal pigment epithelial cells. | Granner, T., et al. 2013. Br J Ophthalmol. 97: 371-4.2622-14-2 supplier PMID: 23292926Production of a chiral alcohol, 1-(3,4-dihydroxyphenyl) ethanol, by mushroom tyrosinase.PMID:33713255 | Brooks, SJ., et al. 2013. Biotechnol Lett. 35: 779-83. PMID: 23355036Antitumor Perspectives of Oleuropein and Its Metabolite Hydroxytyrosol: Recent Updates. | Imran, M., et al. 2018. J Food Sci. 83: 1781-1791. PMID: 29928786Antioxidant Effect of Hydroxytyrosol, Hydroxytyrosol Acetate and Nitrohydroxytyrosol in a Rat MPP+ Model of Parkinson′s Disease. | Pérez-Barrón, G., et al. 2021. Neurochem Res. 46: 2923-2935. PMID: 34260002Hydroxytyrosol [2-(3,4-dihydroxyphenyl)-ethanol], a natural phenolic compound found in the olive, alters Ca2+ signaling and viability in human HepG2 hepatoma cells. | Cheng, HH., et al. 2022. Chin J Physiol. 65: 30-36. PMID: 35229750The protective effect of the olive oil polyphenol (3,4-dihydroxyphenyl)-ethanol counteracts reactive oxygen metabolite-induced cytotoxicity in Caco-2 cells. | Manna, C., et al. 1997. J Nutr. 127: 286-92. PMID: 9039829Inhibition of arachidonate lipoxygenase activities by 2-(3,4-dihydroxyphenyl)ethanol, a phenolic compound from olives. | Kohyama, N., et al. 1997. Biosci Biotechnol Biochem. 61: 347-50. PMID: 9058975