Product Name :
eIF4EBP1 Recombinant Rabbit Monoclonal Antibody [JJ09-25]
Predicted band size :
13 kDa
Observed band size :
17/18 kDa
Synonyms:
4E-BP1 antibody 4EBP1 antibody 4EBP1_HUMAN antibody BP 1 antibody eIF4E binding protein 1 antibody eIF4E-binding protein 1 antibody Eif4ebp1 antibody Eukaryotic translation initiation factor 4E-binding protein 1 antibody PHAS-I antibody PHASI antibody 展开
Function :
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of cap-dependent mRNA translation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide with Human eIF4EBP1 aa 1-49 / 118.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP
Coupling :
unconjugated
Clone number:
JJ09-25
RRID:
AB_3070248
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1-Methylcyclopropaneacetic acid site Aliquot store at -20℃ or -80℃.5458-56-0 Purity Avoid repeated freeze / thaw cycles.PMID:33694125
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 13 kDa
Positive control :
K-562 cell lysate, HepG2 cell lysate, HEK-293 cell lysate, L6 cell lysate, NIH/3T3 cell lysate, Mouse skeletal muscle tissue lysate, Rat skeletal muscle tissue lysate, HepG2, human breast cancer tissue, human colon cancer tissue.