Product Name :
TLR9 Mouse Monoclonal Antibody [H2-B12]
Predicted band size :
Observed band size :
Synonyms:
CD 289 antibody CD289 antibody TLR 9 antibody TLR9 antibody TLR9_HUMAN antibody Toll like receptor 9 antibody Toll like receptor 9 isoform A precursor antibody Toll like receptor 9 isoform B antibody Toll-like receptor 9 antibody
Function :
The Toll-like Receptors (TLR) are a family of human receptors that share homology with the Drosophila Toll Receptors, which are involved in mediating dorsoventral polarization in developing Drosophila embryos and participate in host immunity. The TLR family members are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transductions.947725-04-4 site TLRs are type I transmembrane receptors that contain an extracellular domain consisting of several leucine-rich regions and a single cytoplasmic Toll/IL-1R like domain.77500-04-0 supplier Three TLR family members, TLR7, TLR8 and TLR9, belong to a subfamily of TLRs which are differentially expressed.PMID:33538676 TLR7 is expressed in lung, placenta and spleen. TLR8 is expressed in lung and peripheral blood leukocytes, and TLR9 is predominantly expressed in spleen, lymph nodes, bone marrow and peripheral blood leukocytes. TLR7, TLR8 and TLR9 stimulate the NFκB signaling pathway, suggesting that they play a role in the immune response.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human
Verify application:
WB, ICC, IHC-P, FC
Coupling :
unconjugated
Clone number:
H2-B12
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.
Storage buffer solution:
Purified antibody in PBS with 0.05% sodium azide.
Subtype:
IgG2a
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
116 kDa
Positive control :
Human TLR9 recombinant protein, TLR9-hIgGFc transfected HEK293 cell lysate, SK-OV-3, A549, human ?ovarian cancer tissue, human endometrial cancer tissue.