Product Name :
2-Aminopurine (CAS 452-06-2)
Synonym :
Application :
2-Aminopurine is An inhibitor of PKR.
CAS:
452-06-2
Purity:
≥98%
Molecular Weight:
135.13
Formula :
C5H5N5
Physical state:
Solid
solubility :
Soluble in formic acid:water (1:1 v/v) (50 mg/ml), water, DMSO, hot ethanol, and acid. Insoluble in alkaline solution.
Shipping Condition :
Store at 4° C
Melting point:
280-282° C (lit.)
SMILES:
C1=C2C(=NC(=N1)N)N=CN2
References:
:UV-Fluorescence correlation spectroscopy of 2-aminopurine. | Wennmalm, S., et al. 2001. Biol Chem. 382: 393-7. PMID: 113478862-aminopurine as a probe for quadruplex loop structures. | Gray, RD., et al. 2010. Methods Mol Biol. 608: 121-36. PMID: 200124192-aminopurine as a probe of RNA conformational transitions. | Hall, KB. 2009. Methods Enzymol. 469: 269-85. PMID: 209467942-Aminopurine hairpin probes for the detection of ultraviolet-induced DNA damage. | El-Yazbi, AF. and Loppnow, GR. 2012. Anal Chim Acta. 726: 44-9. PMID: 225410122-Aminopurine as a fluorescent probe of DNA conformation and the DNA-enzyme interface. | Jones, AC. and Neely, RK. 2015. Q Rev Biophys. 48: 244-79. PMID: 25881643Whether 2-aminopurine induces incorporation errors at the DNA replication? A quantum-mechanical answer on the actual biological issue. | Brovarets′, OO. and Pérez-Sánchez, H. 2017. J Biomol Struct Dyn. 35: 3398-3411. PMID: 277946272-aminopurine probe in combination with catalyzed hairpin assembly signal amplification for simple and sensitive detection of microRNA. | Liu, C., et al. 2017. Talanta. 174: 336-340. PMID: 28738589Simple G-quadruplex-based 2-aminopurine fluorescence probe for highly sensitive and amplified detection of microRNA-21. | Li, S., et al. 2018. Talanta. 178: 974-979. PMID: 29136926The Antibiotic Trimethoprim Displays Strong Mutagenic Synergy with 2-Aminopurine. | D′Souza, S., et al. 2019. Antimicrob Agents Chemother. 63: PMID: 30509944A quencher-free 2-aminopurine modified hairpin aptasensor for ultrasensitive detection of Ochratoxin A. | He, Y., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 228: 117780. PMID: 31753651Full liberation of 2-Aminopurine with nucleases digestion for highly sensitive biosensing. | Li, X.BuyFmoc-L-Ala(BCP)-OH , et al.Price of 2387561-40-0 2022.PMID:33745404 Biosens Bioelectron. 196: 113721. PMID: 346734822-Aminopurine Fluorescence Spectroscopy for Probing a Glucose Binding Aptamer. | Lu, C., et al. 2022. Chembiochem. 23: e202200127. PMID: 354682572-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo. | Hu, Y. and Conway, TW. 1993. J Interferon Res. 13: 323-8. PMID: 79055062-Aminopurine induces spindle cell morphology in MM14 myoblasts in the absence of differentiation signals. | Palmer, DK., et al. 1997. Exp Cell Res. 230: 262-74. PMID: 90247852-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases. | Holz, B., et al. 1998. Nucleic Acids Res. 26: 1076-83. PMID: 9461471