Product Name :
VAV3 Recombinant Rabbit Monoclonal Antibody [JE33-02]
Predicted band size :
98 kDa
Observed band size :
98 kDa
Synonyms:
FLJ40431 antibody Guanine nucleotide exchange factor VAV3 antibody Protein vav 3 antibody Protein vav3 antibody RGD1565941 antibody VAV 3 antibody Vav 3 guanine nucleotide exchange factor antibody VAV 3 oncogene antibody VAV 3 protein antibody VAV-3 antibody 展开
Function :
Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases.3-Aminobutan-2-ol Order Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Palladium(II) chloride web VAV3 has been shown to interact with Grb2.PMID:33566786
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human VAV3 aa 748-847 / 847.
Species reactivity:
Human, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE33-02
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 98 kDa
Positive control :
Jurkat cell lysate, HeLa cell lysate, MCF7 cell lysate, rat brain tissue lysate.