Product Name :
TdT Recombinant Rabbit Monoclonal Antibody [PD01-00]
Predicted band size :
Observed band size :
Synonyms:
Deoxynucleotidyltransferase terminal antibody DNA nucleotidylexotransferase antibody DNTT antibody Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody TDT antibody TDT_HUMAN antibody Terminal addition enzyme antibody Terminal deoxynucleotidyltransferase antibody Terminal deoxyribonucleotidyltransferase antibody Terminal transferase antibody
Function :
Terminal deoxynucleotidyl transferase (TdT) is a unique DNA polymerase that changes the addition of deoxynucleoside 5′-triphosphate to the 3′-end of a DNA initiator without template direction. TdT contributes to the generation of junctional diversity in antigen receptors of immature lymphocytes. TdT is expressed in lymphoid precursors of B- and T-cell lineage in thymus and bone marrow. Foci of TdT positive cells maybe observed in peripheral lymphoid tissues. TdT is also present in malignant tumors of lymphoblastic lineage and thymoma. It is a sensitive and specific marker for lymphoblastic lymphoma/leukemia. Anti-TdT is a useful marker for lymphoblastic lymphomas and has been observed in some cases of acute myeloid leukemia.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide.
Species reactivity:
Human
Verify application:
IHC-P
Coupling :
unconjugated
Clone number:
PD01-00
RRID:
AB_3072331
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 1329035-82-6 Aliquot store at -20℃.Buy3-Penten-2-one Avoid repeated freeze / thaw cycles.PMID:33461415
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 59 kDa
Positive control :
Human thymus tissue.