O calcidiol (25-hydroxyvitamin D, 25(OH)D) mainly by the cytochrome enzymes
O calcidiol (25-hydroxyvitamin D, 25(OH)D) mainly by the cytochrome enzymes CYP2R1 and CYP27A1, and subsequent carbon-1-hydroxylation by CYP27B1/1-hydroxylase . The CYP24A1/24-hydroxylase regulates and inactivates 1,25(OH)2D or 25(OH)D in kidney, skin,…