Product Name :
Phospho-c-Jun (S73)+JunD (S100) Recombinant Rabbit Monoclonal Antibody [JE65-46]
Predicted band size :
40/45 kDa
Observed band size :
40/45 kDa
Synonyms:
Activator protein 1 antibody AP 1 antibody AP-1 antibody AP1 antibody cJun antibody Enhancer Binding Protein AP1 antibody Jun Activation Domain Binding Protein antibody JUN antibody Jun oncogene antibody JUN protein antibody 展开
Function :
Transcription factor that recognizes and binds to the AP-1 consensus motif 5′-TGA[GC]TCA-3′. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5′-TGA[GC]TCA-3′ and enhancing its transcriptional activity. Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. (Microbial infection) Upon Epstein-Barr virus (EBV) infection, binds to viral BZLF1 Z promoter and activates viral BZLF1 expression.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phosphopeptide corresponding to residues around Ser73 of human c-Jun.5-Benzylthio-1H-tetrazole Purity
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE65-46
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.55750-62-4 Price 4), 0.PMID:33467936 05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 40/45 kDa
Positive control :
HeLa cell lysate, HeLa treated with 25μg/mL anisomycin for 30 minutes cell lysate, NIH/3T3 cell lysate, NIH/3T3 treated with 25μg/mL anisomycin for 30 minutes cell lysate, RAW264.7 cell lysate, PC-12 cell lysate.